Alogliptin dose range
Web-----DOSAGE AND ADMINISTRATION----- The recommended dose in patients with normal renal function or mild renal impairment is 25 mg once daily. (2.1) ... 59 upper limit of normal (ULN) were observed: 1.3% in alogliptin-treated patients and 1.5% 60 in all comparator-treated patients. 61 Patients with type 2 diabetes may have fatty liver disease ... WebAcross alogliptin doses, mean peak DPP-4 inhibition ranged from 93% to 99%, and mean inhibition at 24 hours after dosing ranged from 74% to 97%. Exposure to active GLP-1 …
Alogliptin dose range
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WebA single-dose of 50 mg alogliptin was administered to 4 groups of patients with varying degrees of renal impairment (creatinine clearance (CrCl) using the Cockcroft-Gault formula): mild (CrCl = > 50 to ≤ 80 mL/min), moderate (CrCl = ≥ 30 to≤ 50 mL/min ), severe (CrCl = < 30 mL/min) and End-Stage Renal Disease (ESRD) on haemodialysis. WebObserve patients with renal disease receiving alogliptin for signs and symptoms of heart failure and/or worsening renal impairment. Adjust alogliptin dosage if indicated based …
WebIt is usually taken with or without food once a day. Take alogliptin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take alogliptin exactly as directed.
WebFeb 1, 2024 · The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. WebFeb 3, 2011 · Has a body mass index between acceptable range. Is experiencing inadequate glycemic control. Body weight keeps constant. Females of childbearing potential and males who are sexually active agree to use routinely adequate contraception from signing of informed consent throughout the duration of the study and for 30 days after …
WebMay 13, 2024 · Take alogliptin tablets exactly as your doctor tells you to. Your dose will be on the label of the pack to remind you about what the doctor said to you. If you are taking …
WebAlogliptin: 12.5 mg once daily if estimated glomerular filtration rate (eGFR) is 30–50 mL/minute/1.73 m 2. Reduce to 6.25 mg once daily if eGFR is less than 30 … forklift rental chicago ilMild Renal Impairment (CrCl 60 mL/min or greater): No adjustment recommended Moderate Renal Impairment (CrCl 30 to 60 mL/min): 12.5 mg orally once a day Severe Renal Impairment (CrCl 15 mL to less than 30 mL/min): 6.25 mg orally once a day ESRD (CrCl less than 15 mL/min): 6.25 mg orally once … See more Usual dose: 25 mg orally once a day Comments: When used in combination with insulin or insulin secretagogues such as sulfonylureas, a lower dose of insulin or the insulin … See more Safety and efficacy have not been established in patients younger than 18 years. Consult WARNINGS section for additional precautions. See more Mild to moderate liver dysfunction (Child-Pugh Grade A and B): No adjustment recommended Severe liver dysfunction (Child-Pugh C): Data … See more If used in combination with insulin or an insulin secretagogue such as sulfonylureas, a lower dose of insulin or the insulin … See more difference between islam and christianityWebFor alogliptin Dose adjustments Reduce dose to 12.5 mg once daily if creatinine clearance 30–50 mL/minute. Reduce dose to 6.25 mg once daily if creatinine clearance less than … forklift rental corpus christiWebFeb 1, 2024 · Descriptions. Alogliptin is used together with proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes. Alogliptin helps to control blood … difference between islam and muslim religionWebFeb 1, 2024 · Vipidia 6.25mg, 12.5mg, 25mg film-coated tablets Active Ingredient: alogliptin benzoate Company: Takeda UK Ltd See contact details About Medicine Prescription … forklift rental companies near meWebMar 1, 2024 · Adults—At first, 1 tablet 2 times a day. Each tablet contains 12.5 milligrams (mg) of alogliptin and 500 mg of metformin or 12.5 mg of alogliptin and 1000 mg of metformin. Your doctor may adjust your dose as needed. However, the dose is usually not more than 25 mg of alogliptin and 2000 mg of metformin per day. difference between islam and sharia lawWebAlogliptin (Nesina) dosage forms tablet 6.25mg 12.5mg 25mg Typical dosing for alogliptin (Nesina) The typical dose is 25 mg taken by mouth once daily. Your dose may differ if … forklift rental corpus christi tx