Refractory to platelet transfusion
Web5. dec 2015 · One study estimated the total activity-based cost of RBC transfusion as $761 (in 2008 dollars). 18 Extrapolating to platelet transfusion, the total cost of platelet transfusion would be greater than $1,000 because of higher acquisition costs. A typical large hospital transfuses more than 30,000 RBC units and 10,000 platelets per year. Web19. okt 2014 · CONCLUSIONS: HLA and/or HPA alloimmunisation is an important factor to cause refractoriness to platelet transfusions. Crossmatch-compatible platelet transfusion is an effective method in those patients refractory to random platelet transfusions. Full text links Read article at publisher's site (DOI): 10.1111/tme.12157 References
Refractory to platelet transfusion
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Web1. apr 2014 · Alloimmunized refractory patients are a significant challenge for blood transfusion services as they are Correspondence: Nicoletta Revelli, DSc, Department of Transfusion Medicine and Hematology ... Web31. jan 2024 · If RhD-positive platelets are transfused to a RhD-negative female of childbearing age, prevention of RhD with immunisation should be considered Following HLA or HPA alloimmunisation patients may become refractory to platelet transfusion or have significantly shortened survival of the same. HLA-compatible or HPA-matched may be …
WebPlatelet transfusion refractoriness is the repeated failure to achieve the desired level of blood platelets in a patient following a platelet transfusion. The cause of refractoriness … Web17. nov 2024 · A previously recognized finding in the TRAP study was the more platelet transfusions a patient received, the lower were their post-transfusion platelet increments . Our study shows that the higher the dose of CD34+ cells infused with the hematopoietic grafts the lower was the probability to become platelet transfusion refractory.
Web24. jan 2024 · Platelet transfusion: Indications, ordering, and associated risks; ... Bourgeois E, Caulier MT, Delarozee C, et al. Long-term follow-up of chronic autoimmune thrombocytopenic purpura refractory to splenectomy: a prospective analysis. Br J Haematol 2003; 120:1079. WebPatients who are refractory to platelet transfusions because of alloimmunization may benefit from HLA-matched or crossmatch-compatible platelets because these platelets are presumed to lack antigen(s) against which the patient has formed antibodies.
WebRefractory: rituximab Autoimmune hemolytic anemia: glucocorticoids plus immunosuppressive therapy Monitor and treat infection, especially in patients with …
Web1. júl 2024 · Platelets are transfused to prevent or treat bleeding associated with thrombocytopenia or platelet dysfunction. In adults, 1 unit of apheresis platelets … the angel experiment seriesWebThe most common cause of refractoriness is contamination of the platelet product with leukocytes, resulting in human leukocyte antigens antibody formation. ABO … the angel experiment summaryWebClass I HLA antigens on platelets are a known cause for platelet refractoriness. Leukoreduction of blood products is used as a mechanism to reduce or prevent patients … the gate web clientWeb2. feb 2024 · The patient is in platelet refractory state as demonstrated by the failure to achieve an expected platelet count increment within an hour of transfusion on multiple … the angel eyesWeb18. sep 2024 · No hemolysis was reported, and 1 platelet transfusion reaction was observed. At Mount Sinai, no transfusion adverse events were observed, no new unexpected RBC alloantibodies were identified, and transfusions increased hemoglobin values (median, 1.2 g/dL). ... In the treatment setting of relapsed and refractory MM, where patients are … the gate wedding cornwallWebIn conclusion, platelet transfusion refractoriness requires 2 or more inappropriate responses to platelets as defined by below normal PPR or CCI. Platelet transfusion refractoriness is … the gate wheelWeb28. sep 2024 · Such platelet transfusion–refractory patients can be effectively managed with appropriate antigen-negative products. STUDY DESIGN AND METHODS. Our … the angel face