Semaphorin 3a是什么
Web生物物理所感染与免疫海外团队揭密人类信号素 (Semaphorin)免疫调节新机制. Semaphorin是一大类分泌型或跨膜型糖蛋白分子，参与机体多项重要生理过程的调节，包括调控神经系统的轴突发育，血管形成, 骨分化,心血管发育等。. 根据其组成特点将其分为8型。. … WebMay 26, 2024 · Takahashi, T. et al. Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell 99 , 59–69 (1999). Article CAS PubMed Google Scholar
Semaphorin 3a是什么
Did you know?
Web康朗生物为您提供sh2结构域蛋白3a抗体的参数及2024年最新报价，厂家专业的sh2结构域蛋白3a抗体售后服务团队，是您值得信赖的合作伙伴 您好，欢迎访问仪器信息网 WebSemaphorin 3A is a secreted disulfide-bound homodimer involved in the nervous system in growth cone collapse and axon growth repulsion. Recently, recombinant semaphorin 3A was used to study effects on platelets, which have some characteristics similar to neurons. Functional semaphorin 3A receptors were detected on platelets, and dose-dependent ...
WebDec 10, 2024 · Semaphorin 3A (Sema3A), known for its axon guidance and antiangiogenic properties, has been implicated in GBM growth. We hypothesized that Sema3A directly … http://www.ibp.cas.cn/kyjz/2024kyjz/202404/t20240426_5003163.html
WebJan 14, 2024 · Abstract Semaphorin-3A (Sema-3A), a secreted member of the semaphorin family, is well known for playing regulatory functions at all stages of the immune response. Sema-3A transduces signals by binding to its cognate receptors, namely, class A plexins (Plxns A1 to A4) and neuropilin-1 (Nrp-1). The downstream diverse signaling pathways … WebBone remodeling occurs at the bone surface throughout adult life and associates bony quantity and quality. This process is a balance between the osteoblastic bone formation and osteoclastic bone resorption, which cross-talks together. Semaphorin 3A is a membrane-associated secreted protein and regarded as a diffusible axonal chemorepellent, which …
WebJul 3, 2006 · The eight main classes of semaphorins [] differ in sequence and overall structural characteristics, but all members of the family contain a conserved extracellular domain of about 500 amino acids termed the semaphorin (sema) domain (Figure 2).This domain shows considerably higher conservation among the different semaphorins and …
WebAug 1, 2014 · Semaphorin 3A and semaphorin 3E appear to promote particular diseases of the microvasculature, and therapies that target these semaphorins and their downstream signalling events may be promising ... butchery comboWebSep 30, 2024 · Our study identifies in MS patients the overexpression of Plexin-A1, the signalling receptor of the oligodendrocyte inhibitor Semaphorin 3A. Using a novel type of peptidic antagonist, we showed the possibility to counteract the Sema3A inhibitory effect on oligodendrocyte migration and differentiation in vitro when antagonizing Plexin-A1. butchery collegeThe SEMA3A gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted Semaphorin-3A protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, … See more Semaphorin-3A is a protein that in humans is encoded by the SEMA3A gene. See more The protein semaphorin-3A is highly expressed in scar tissue after traumatic central nervous system injuries, such as spinal cord injury. … See more • SEMA3A human gene location in the UCSC Genome Browser. • SEMA3A human gene details in the UCSC Genome Browser. See more • Schmidt EF, Strittmatter SM (2007). "The CRMP family of proteins and their role in Sema3A signaling". Semaphorins: Receptor and Intracellular Signaling Mechanisms. Adv. Exp. Med. Biol. … See more ccw safety coursebutchery company profileWeb抗体/抗原 elisa试剂盒 常用生化试剂 实验材料 蛋白质/多肽 微生物 临床与卫生标准物质/标准品 有机溶液标准物质/标准品 ccw safe vs firearms legal protectionWebMar 29, 2024 · Summary. This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. butchery colesbergWebMar 21, 2012 · Lorem ipsum 是指一篇常用于排版设计领域的拉丁文文章，主要的目的为测试文章或文字在不同字型、版型下看起来的效果。. Lorem ipsum从西元15世纪开始就被广 … ccw safe website